I-APIS ithetha into eyikhemikhali ebonelelwe ngokukodwa ukuveliswa kwamalungiselelo amayeza;ii-APIs eziyinyumba zezo zingenayo nayiphi na i-microorganisms esebenzayo, enjenge-molds, ibhaktheriya, iintsholongwane, njl.
i-serile API sisiseko kunye nomthombo wamashishini okulungisa amayeza, kwaye inqanaba lokuqinisekisa umgangatho wemveliso yalo lihambelana ngokuthe ngqo nokhuseleko lwamachiza; Ukuhambelana kweekhemikhali zecandelo lokucoca kufunwa ngokungqongqo kwinkqubo yokucoca ulwelo kunye noninzi lwe-solvent. , ngakumbi ukuhluzwa kwe-solvent edliwayo.I-Kinda Filtration idityaniswe neenkonzo zayo zokuqinisekisa inkqubo yelabhoratri, ukubonelela ngamashishini amayeza kunye nenkqubo yokuvelisa rhoqo ngokuhambelana nemigangatho emiselweyo kunye neempawu zomgangatho weemveliso zokucoca.
Ngokomthombo wayo, i-APIS yahlulahlulwe ngamachiza okwenziwa kweekhemikhali kunye neziyobisi zendalo.
Amachiza okwenziwa kweekhemikhali anokohlulwa abe ngamachiza enziweyo angenziwanga kunye namachiza enziweyo.
Iziyobisi zokwenziwa kwe-inorganic zikhompawundi ze-inorganic, ezifana ne-aluminium hydroxide kunye ne-magnesium trisilicate kunyango lwesilonda sesisu kunye ne-duodenal, njl.
Amachiza okwenziwa kwe-Organic enziwa ikakhulu ngezinto ezisisiseko zemichiza ekrwada, ngothotho lweempendulo zemichiza ephilayo kunye neziyobisi (ezifana ne-aspirin, i-chloramphenicol, i-caffeine, njl.).
Iziyobisi zendalo zekhemikhali zinokwahlulwa zibe ngamachiza e-biochemical kunye neziyobisi ze-phytochemical ngokwemithombo yazo.Ii-antibiotics ziveliswa ngokubanzi ngokuvutshelwa kwe-microbial kwaye ziyinxalenye ye-biochemistry.Kwiminyaka yakutshanje, iintlobo ezininzi ze-semi-synthetic antibiotics ziyindibaniselwano ye-biosynthesis kunye neemveliso ze-chemical synthesis.Phakathi kwe-apis, i-organic synthetic drug zenza owona mlinganiso mkhulu weentlobo ezahlukeneyo, isivuno kunye nexabiso lemveliso, eyona ntsika iphambili kwishishini loxubo lwamayeza.Umgangatho we-API unquma umgangatho wokulungiselela, ngoko imigangatho yayo yomgangatho ingqongqo kakhulu.Onke amazwe ehlabathi aqulunqe imigangatho engqongqo ye-pharmacopoeia kazwelonke kunye neendlela zokulawula umgangatho we-APIS esetyenziswa kakhulu.